小任班长 发布的文章

The government work report said that no specific target for the annual economic growth rate was proposed, mainly because the global epidemic situation and the economic and trade situation are highly uncertain, and China's development is facing some unpredictable factors. In doing so, it is helpful to guide all parties to concentrate on "six stability" and "six guarantees". "Six Guarantees" is the focus of this year's "Six Stability" work. Keeping the bottom line of the "six guarantees" can stabilize the economic fundamentals; to promote stability and make progress through stability, we can lay a solid foundation for building a well-off society in an all-round way.
government work report

This year's deficit rate is planned to be set at more than 3.6%. The fiscal deficit scale will increase by 1 trillion yuan compared with last year. At the same time, 1 trillion yuan of special anti-epidemic bonds will be issued.

sqlserver创建发布分发服务器时提示目录无效的解决办法

错误详情:
SQL Server 无法将“xx”配置为分发服务器。

其他信息:
执行 Transact-SQL 语句或批处理时发生了异常。 (Microsoft.SqlServer.ConnectionInfo)

目标路径 D:MSSQLDATA 无效。无法列出目录内容。请指定有效的目标路径。
已将数据库上下文更改为 'master'。 (Microsoft SQL Server,错误: 14430)

有关帮助信息,请单击: http://go.microsoft.com/fwlink?ProdName=Microsoft+SQL+Server&ProdVer=10.50.1600&EvtSrc=MSSQLServer&EvtID=14430&LinkId=20476

尝试修改文件夹权限,未果。

解决方法:

打开sqlserver配置管理器,查看启动sqlserver的账户应该是NetWorkService修改成LocalSystem最高权限即可。
修改后,会自动重启sqlserver服务。具体操作见图

修改sqlserver服务启动账户

方法一

报错提示一般是多了个空格,将新加的配置多余空格删除即可。

方法二

若配置文件确实没问题,可能conf文件被记事本编辑过,保存成了含[BOM] 。所以才报错的。

解决办法
使用editplus 等其它非记事本 另存为 UTF-8 不含BOM 的文件就可以了。

nginx unknown directive

The Chinese scientific research team recently published a paper online in the United States "Science" magazine that they found two human monoclonal antibodies that can effectively block the infection of the new coronavirus, which is expected to be used in the development of anti-new crown drugs and vaccines.

Many units including the Capital Medical University of China, the Institute of Microbiology of the Chinese Academy of Sciences, the Tianjin Institute of Industrial Biotechnology of the Chinese Academy of Sciences, and the Third People's Hospital of Shenzhen participated in this study.

The researchers isolated four human monoclonal antibodies from the peripheral blood mononuclear cells of a newly rehabilitated patient.

new coronavirus

Experiments show that these four antibodies have the ability to neutralize the new coronavirus. Among them, two antibodies called B38 and H4, respectively, can block the binding of the receptor binding domain of the new crown virus spike protein and its receptor "Angiotensin Converting Enzyme 2 (ACE2)".

A number of previous studies that revealed the infection mechanism of the new coronavirus have shown that the virus mainly achieves infection through the binding of its spike protein receptor binding domain to ACE2 on human cells.

Experiments have shown that B38 and H4 respectively recognize different epitopes of the receptor binding domain. Mouse experiments confirmed that these two antibodies can reduce the amount of virus infecting the lungs of mice, showing a therapeutic effect. The two antibodies can also be used in combination to more effectively suppress viral infections.

The research team further analyzed the structure of the complex formed by the new crown virus spike protein receptor binding region and B38, thus revealing the molecular mechanism of B38 blocking viral infection.

Researcher Introduction

The latest research shows that the two antibodies screened have the potential to be further developed into new coronavirus infection drugs, and provide a basis for vaccine design. At present, the two antibodies have been transformed into products by related companies, and are expected to be used for clinical treatment of patients with new crowns in the future.

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